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Clinical Data
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Sleep-Inducing Effects of Melatonin
Sleep-Inducing Effects of Low Doses of Melatonin Ingested in the Evenings
(Harvard Medical School and MIT) Clinical Pharmacology & Therapeutics, 1995.
Learn MoreEffects of Exogenous Melatonin on Sleep: A Meta-Analysis
(MIT, Boston University School of Medicine, University of Glasgow, UK, and Hadassah Medical Center, Israel) Sleep Medicine Reviews, 2005.
Learn MoreMeta-Analysis: Melatonin for the Treatment of Primary Sleep Disorders
(Yale University, Children’s Hospital of Michigan, and University of São Paulo Medical School) PLOS One, 2013.
Learn MoreProlonged-Release Melatonin
Prolonged-Release Melatonin Improves Sleep Quality and Morning Alertness in Insomnia Patients Aged 55 Years and Older and Has No Withdrawal Effects
(The Clinique Lyon-Lumière, France; Neurim Pharmaceuticals, Israel; Tel Aviv University, Israel) Journal of Sleep Research, 2007.
Learn MoreProlonged-Release Melatonin for Insomnia – An Open-Label Long-Term Study of Efficacy, Safety, and Withdrawal
(The Clinique Lyon- Lumière, France; Shoham Geriatric Medical Center, Israel; Neurim Pharmaceuticals, Israel; Tel Aviv University, Israel) Therapeutics and Clinical Risk Management, 2011.
Learn MoreSafety
Nightly Treatment of Primary Insomnia with Prolonged Release Melatonin for 6 Months: A Randomized Placebo Controlled Trial on Age and Endogenous Melatonin as Predictors of Efficacy and Safety
(University of Glasgow, UK; Tel Aviv University, Israel; and CPS Research, UK) BMC Medicine, 2010.
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