News & Events

See the advanced science behind the first and only continuous-release and absorption melatonin study approved after peer review and then published.

Wobenzym® News & Events


Summary Expert Panel


REMfresh® Patient Reported Outcomes Studies

1600 patients across three real world studies demonstrated significant improvements in sleep offset, duration, maintenance and quality.

SLEEP 2019

REMfresh® Duration Validation (REMVAL) and REMfresh® Short Sleep Cohort Assessment (REMSS)

SLEEP 2018

REMfresh® Patient-Reported Outcomes DURation (REMDUR)

SLEEP 2017

REM Absorption Kinetics Trial (REMAKT)


No Pattern Of Side Effects... No Concern on Safety Profile

REMSU24 (REMfresh® Safety Update at 24 Months) - an adverse event reporting rate of only 0.016% with no serious adverse events reported in an estimated 320,255 patients.


Quality Ingredients, Pharmaceutical-Quality Manufacturing

Made with UltraMel®, a 99% ultrapure melatonin sourced from Western Europe, where melatonin is regulated as a drug.

Part of an FDA Drug Master File.

Manufactured in FDA-inspected facilities (cGMP standards).

Your Nightly Sleep Companion®

Supports up to 7 hours of quality sleep.